Description
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-c) is a mitochondria-derived peptide under active investigation for its role in metabolic regulation, cellular stress response, and aging research. This 16-amino acid peptide is encoded within the mitochondrial genome and functions as a signaling molecule linking mitochondrial activity to nuclear gene expression and systemic metabolic adaptation.
Each 10 mg vial contains lyophilized MOTS-c powder with verified purity of ≥98% (HPLC). The peptide is supplied as a synthetic research-grade compound designed for advanced laboratory and analytical applications.
Research applications include the study of metabolic homeostasis, insulin sensitivity, exercise physiology, stress resistance, and mitochondrial signaling pathways. MOTS-c has been shown in laboratory models to translocate to the nucleus under metabolic stress, where it can activate adaptive gene expression programs and influence pathways related to glucose utilization, fatty acid oxidation, and oxidative stress response.
Mechanistic research suggests MOTS-c plays a role in regulating AMPK signaling, insulin action, and mitochondrial communication with the nucleus. Investigations also focus on its potential involvement in age-related metabolic decline, exercise performance, and resistance to metabolic stressors.
This material is supplied specifically for advanced laboratory and analytical research in the fields of cellular metabolism, mitochondrial biology, and aging mechanisms. Proper storage at –20 °C or below is recommended; when stored accordingly, the peptide maintains stability for up to 24 months.
This product is intended exclusively for in-vitro scientific investigation. No claims are made regarding safety, efficacy, or suitability for diagnostic, therapeutic, or dietary use.
For laboratory research use only. Not for human or veterinary consumption.
